SKIN CREAM Basic science

FROM HEART RESEARCH TO SKIN CREAM - UMass Medical School directory | contacts | index this section only "/ Home News Bureau News Makers Publications Community Relations Logos & Photography public affairs and publications : news : 2004 FROM HEART RESEARCH TO SKIN CREAM Basic science research on cellular functions yields a surprising discovery November 1, 2004 WORCESTER, Mass.- The observation came during their work studying cellular processes within the heart. In that effort, University of Massachusetts Medical School (UMMS) scientists James G. Dobson, Jr., PhD, professor of physiology and medicine, and Michael F. Ethier, PhD, assistant professor of medicine, were probing the effects of aging on heart function. Little did they realize that their work with adenosine would lead to the creation of a cream that improves skin tone and diminishes wrinkles. "The results took us completely by surprise, but that's what happens in basic science work," Dr. Dobson said. "The science often leads us down unexpected paths." Adenosine is a naturally occurring nucleoside found in many cells of the body. Among its other attributes, adenosine is known to play a role in helping the heart muscle and vascular walls contract and relax. Drs. Dobson and Ethier were studying adenosine in a series of experiments probing the effect of aging on the cellular functions within the heart. "In that work, we began using dermal fibroblasts, which are skin cells, because they have well-defined aging characteristics," Dr. Ethier said. "Skin cells will only divide a certain number of times in culture, and then they die. And younger human skin cells will divide more times than older skin cells, so it's a good research model." As the experiments on heart function progressed, however, the team noticed that when adenosine was added to the skin cells, protein production within the cells increased and the cells grew in size. The observation had a clear correlation with human skin health and wrinkles, given that it is well known that as people age their skin cells decrease in size and gradually lose their ability to synthesize proteins such as collagen and elastin. Additional work by the two scientists suggested that adenosine may mitigate another age-related effect on skin- the dramatic decline in the number of capillaries supplying blood to the dermis (the connective tissue layer of the skin located below the surface.) Growth of new capillaries is dependent on the proliferation of endothelial cells which line the inside of all blood vessels. In a series of experiments, Dobson and Ethier showed that adenosine stimulated proliferation of human endothelial cells. Results of these experiments have been presented at meetings of The American Federation for Experimental Biology and The International Symposium on Adenosine and Adenine Nucleotides- papers on this science have been published in the Mechanisms of Ageing and Development, American Journal of Physiology and Experimental Gerontology. In July of 2002 and in November of 2003, U.S. patents were issued to UMMS for Dobson and Ethier's technology for the application of adenosine and adenosine analogs for skin treatment. While related patent applications were pending in territories outside of the United States, Hankook Cosmetics Company, Ltd. of Seoul, South Korea, developed an interest in the technology. In 1999, UMMS entered into a license agreement with Hankook Cosmetics Company, Ltd., for the exclusive development, manufacture and distribution of adenosine-based skin care products within the South Korean marketplace. In 2000, Hankook funded independent human studies in South Korea that showed topical application of adenosine decreased skin's propensity to stretch and reduced wrinkle depth. The company launched its first adenosine-based product line in 2001. "Their clinical data is quite impressive," Dobson said. "Many thousands of people in South Korea have used this product, and it works quite well." To bring adenosine-based products to a broader market, UMMS signed an exclusive license agreement in July of this year with IGI Inc. of Buena, New Jersey, developers of the patented Novasome® transdermal delivery system that encapsulates and administers therapeutic topical products. "IGI is pleased to add adenosine to its growing portfolio which includes PTH (1-34) for the treatment of psoriasis and PTH (7-34) for alopecia," said Frank Gerardi, IGI's chairman and CEO. "We intend to use adenosine to create a new product for the treatment of skin conditions." # # # The University of Massachusetts Medical School, one of the fastest growing medical schools in the country, has built a reputation as a world-class research institution, consistently producing noteworthy advances in clinical and basic research. UMass Medical School and its clinical partner, UMass Memorial Health Care, attract more than $154 million in research funding annually, 80 percent of which comes from federal funding sources. Research funding enables UMMS researchers to explore human disease from the molecular level to large-scale clinical trials. Contact: Michael Cohen 508-856-2000 michael.cohen@umassmed.edu INTRANET top print This is an official Page/Publication of the University of Massachusetts Worcester Campus Public Affairs and Publications 55 Lake Avenue North Worcester, MA 01655 Questions or Comments? Email: PublicAffairs@umassmed.edu Phone: (508) 856-2000

skin rash (erythema migrans)

Yahoo! Health Lyme disease skin rash (erythema migrans) Home Healthy Living Diseases & Conditions Health News Groups & Boards Drug Guide Site Index Search All Yahoo! Health The Web Top New Year's Searches on Yahoo! Health: resolutions , weight loss , healthy habits , fitness Want to Lose Weight? Marilu Henner helps you shed the unwanted pounds. GET FIT IN 2006 with tips from Gabrielle Reece and other experts. Sponsored by: NIKEWOMEN.COM Encyclopedia provided by: Healthwise A A-Ag Ah-Ap Aq-Az B B-Bg Bh-Bp Bq-Bz C C-Cg Ch-Cp Cq-Cz D D-Dg Dh-Dp Dq-Dz E E-Eg Eh-Ep Eq-Ez F F-Fg Fh-Fp Fq-Fz G G-Gg Gh-Gp Gq-Gz H H-Hg Hh-Hp Hq-Hz I I-Ig Ih-Ip Iq-Iz J J-Jg Jh-Jp Jq-Jz K K-Kg Kh-Kp Kq-Kz L L-Lg Lh-Lp Lq-Lz M M-Mg Mh-Mp Mq-Mz N N-Ng Nh-Np Nq-Nz O O-Og Oh-Op Oq-Oz P P-Pg Ph-Pp Pq-Pz Q Q-Qg Qh-Qp Qq-Qz R R-Rg Rh-Rp Rq-Rz S S-Sg Sh-Sp Sq-Sz T T-Tg Th-Tp Tq-Tz U U-Ug Uh-Up Uq-Uz V V-Vg Vh-Vp Vq-Vz W W-Wg Wh-Wp Wq-Wz X X-Xg Xh-Xp Xq-Xz Y Y-Yg Yh-Yp Yq-Yz Z Z-Zg Zh-Zp Zq-Zz 0-9 0-2 3-6 7-9 Lyme disease skin rash (erythema migrans) Topic Contents Lyme disease skin rash (erythema migrans) Credits Email this article Print this article Lyme disease skin rash (erythema migrans) Most people who get Lyme disease develop a red rash called erythemamigrans (EM) within a month after the tick bite. The average length of timebefore the rash appears is 7 to 14 days, but symptoms can develop anywhere from3 to 31 days after being bitten. The rash usually starts as a small red area and then expands over the course of several days. It may grow to be 1 ft (0.3 m) across. Sometimes the rash clears in the center, so that it looks like a bull's-eye. The rash may be warm to the touch, but it is usually not painful or itchy. Common sites for the rash include the thighs, groin, trunk, armpits, waistline, and behind the knees. The rash is easy to miss if it is in an area you can't see, such as the scalp or buttocks, which are common rash sites in children. You also are more likely to miss ticks that have attached in these areas. Patches of red rash may develop elsewhere as the Lyme disease bacteria circulate through the blood and come to rest in other areas of the skin. The rash usually fades within 3 to 4 weeks even if you are not treated for Lyme disease. (back to top) Credits Author Dana L. Rowett Editor Renée Spengler, RN, BSN Associate Editor Lila Havens Associate Editor Tracy Landauer Primary Medical Reviewer Adam Husney, MD - Family Medicine Specialist Medical Reviewer W. David Colby, MSc, MD, FRCPC - Infectious Disease Last Updated September 20, 2004 (back to top) Author: Dana L. Rowett Medical Review: Adam Husney, MD - Family Medicine W. David Colby, MSc, MD, FRCPC - Infectious Disease Last Updated: September 20, 2004 Sponsored Links Fresh Cuisine(TM) - Your Personal Diet Chef Healthy fresh meals. Chef prepared, delivered nationwide. 1 free week. www.freshcuisine.com Teach Healthy Eating Habits to Childs Take the free years ahead test and find out how you can become a better parent. Get tips, info and a personal action plan to help you raise healthy, well-balanced kids. www.yearsahead.com Lose Weight the Healthy Way We cook the food, you lose the weight. Our meals are chef prepared and physician approved. We deliver at your door steps. Convenience, quality and results. Healthy eating. www.diettoyourdoor.com ( What's this? ) Email this article Print this article © 1995-2005, Healthwise, Incorporated, P.O. Box 1989, Boise, ID 83701. ALL RIGHTS RESERVED. This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.For more information, click here . Privacy Policy . How this information was developed . Not finding what you're looking for? Send Feedback This site does not provide medical or any other health care advice, diagnosis or treatment. The site and its services, including the information above, are for informational purposes only and are not a substitute for professional medical advice, examination, diagnosis or treatment. Always seek the advice of your physician or other qualified health professional before starting any new treatment or making any changes to existing treatment. Do not delay seeking or disregard medical advice based on information on this site. Medical information changes rapidly and while Yahoo! and its content providers make efforts to update the content on the site, some information may be out of date. No health information on Yahoo! , including information about herbal therapies and other dietary supplements, is regulated or evaluated by the Food and Drug Administration and therefore the information should not be used to diagnose, treat, cure or prevent any disease without the supervision of a medical doctor.

Face Scrub # Of

Robbie's Bath & Body Recipes: Honey & Lemon Face Scrub Buy The Cookbook! Copycat Recipes Appetizers & Snacks Pasta Dishes Desserts & Baked Goods Meats Chicken & Turkey Seafood & Fish Salads & Dressings Soups, Chilis & Chowder s Side Dishes Fruits & Vegetables Pizza & Related Recipes Condiments Beverages Breakfast Foods Pet Treat Recipes Bath & Beauty Recipes Submit Your Recipe Request A Recipe Robbie's Kitchen Household Tips & Tricks Cooking Tips Cleaning Tips Laundry Tips Home Remedies Pet Home Remedies Message Board Learn Fancy Napkin Folds Ingredient Substitutions Measurement Equivalents Measurement Conversion Temperature Conversion Meat Temperatures Candy Temperatures Robbie's Photo Album Pet Health Search This Site Contact Robbie Honey & Lemon Face Scrub # Of Applications: 1 Prep. Time: 0:10 1 med. lemon - juice of 2 Tbls. finely ground almonds 1 Tbls. honey -Combine all ingredients. -Massage mixture into face and neck. -Leave on for 5 minutes. -Rinse off with warm water. (3) Visitor Comments: I use this without the almonds. It stung at first, but clears up your skin! i used this recipe today...but a little variance. i had no fresh lemon so i used a tlbs. lemon juice and i used 3-4 tlbs. finely ground almonds to make it thicker so it wouldn't run. it made my skin very smooth but didn't instantly help out with small blemishes (not to be expected though). thanks a lot! I tried this with a friend and we loved it. it made our skin soft and silky! Related Books Natural Beauty at Home 200+ Easy-To-Use Recipes for Body, Bath, and Hair The Herbal Body Book A Natural Approach to Healthier Skin, Hair, and Nails Natural Beauty for All Seasons More Than 250 Simple Recipes and Gift-Giving Ideas for Year-Round Beauty Jude's Herbal Home Remedies Natural Health, Beauty & Home-Care Secrets Do not reproduce or reprint content within this web site without consent from the Webmaster .

Bady Care

Percy Bady - Percy Bady Experience - Tracks - Yahoo! Shopping Primary Navigation Home Computers Clothing Electronics Home & Garden Valentine's Day Flowers DVDs More My Shopping Automotive Auctions Bargains & Sales Beauty & Fragrances Books & Magazines Clothing, Accessories & Shoes Computers Credit Cards Electronics Flowers & Gifts Health & Personal Care Home & Garden Jewelry & Watches Movies & DVD Long Distance Music Small Business Sports & Outdoors Tickets Tools & Hardware Toys & Baby Travel Video Games Shop By Brand Shop By Store More... Search Music All of Shopping • Advanced Search All_Laptops Percy Bady - Percy Bady Experience : Tracks Compare Prices User Reviews Expert Review Credits Tracks Work Listings Tracks To hear an audio sample, click the song title below. Windows Media player is required. 1. Intro 9. I'll Keep Holding On 2. Medley: Songs That Brought Us Through - There Is Hope/Lord I Believe/Can't Look Back Now/Love Said Not So/The Holy Ghost 10. Father To Son 3. It Was Love 11. Hold Up The Light (Old School Mix) 4. You Oughta Been There 12. Hold Up The Light (Remix) 5. Gone But Not Forgotten 13. Outro 6. Free 14. I'll Keep Holding On 7. Um Good 15. Gone But Not Forgotten 8. Keep On Dreaming 16. Um Good Compare Prices Percy Bady Experience $5.99- $17.98 from 9 merchants Compare Prices Percy Bady Experience $5.99 - $17.98 from 9 merchants Walmart.com $13.88 Overstock.com $13.86 SPONSORED LINKS Percy Bady at Amazon.com Shop Amazon.com for low prices on a vast selection of new and used music. Free Super Saver Shipping on qualified orders over $25. www.amazon.com Percy Bady on Yahoo! Music Check out Percy Bady. Get music downloads. Watch free music videos. See artist photos, live interviews, exclusive performances plus listen to great radio stations - all on Yahoo! Music. music.yahoo.com [ What's this? ] Compare Prices User Reviews Expert Review Credits Tracks Work Listings Auctions Shopping > Music > Percy Bady Experience Search Music All of Shopping • Advanced Search All_Laptops Want to see your products in Yahoo! Shopping? Build your own online store or Advertise with us. Current Advertisers Sign In Help improve Yahoo! Shopping by participating in our user studies - -- ©2006 All Media Guide, LLC Content provided by All Music Guide ® , a trademark of All Media Guide, LLC. Information about prices, products, services and merchants is provided by third parties and is for informational purposes only. Yahoo! does not represent or warrant the accuracy or reliability of the information, and will not be liable for any errors, omissions, or delays in this information or any losses, injuries, or damages arising from its display or use.

Lip Balm WHY IT

Product: Beeswax Lip Balm Contact Us View Cart | Checkout Our Products Lips Face Body Baby Bee Hair Care Oral Care Cosmetics Natural Remedies Gifts & Kits Men's Grooming Burt's Outlet Search Advanced Search Shopping Cart 0 Item(s) in Cart Subtotal : $0.00 Beeswax Lip Balm WHY IT WORKS: This is our most popular product of all. It’s packed with protective ingredients such as ultra emollient lanolin and almond oil to help soothe cracked or chapped lips. You can use it on healthy lips for a little peppermint tingle. You may want to keep one in your pocket, one in your desk and one in your car. Soon, you’ll hold them close to your heart. They’re available in the old-fashioned yellow tin or in a post-consumer recycled plastic tube. HOW IT WORKS: Apply balm liberally to lips as often as needed, particularly in dry, cold or windy conditions. .30 oz. tin, .15 oz. tube List of ingredients. Select Packaging Tin Tube $2.50 Qty: Add to Cart "My husband and I are ADDICTED to Burt's Bees Lip Balm . Got to have it ALL the time. We buy 10 tubes at a time and it is everywhere. We stash it in drawers, pockets, bedside table, in the car, in desk at work, in the purse. When we are out and one of us needs some Burt's Bees Lip Balm , we simply look at one another and say 'Burt me.'" BEESWAX - A natural wax made by bees in the cell walls of honeycombs. Beeswax is a natural emulsifier used in cosmetics. Adds a wonderful natural smell and color, and helps to seal and protect the skin when used to moisturize. Site Map | About the Company | Employment | Privacy © Burt’s Bees Inc. 2005