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Web Services and other distributed technologies Microsoft.com Home | Site Map MSDN Home | Developer Centers | Library | Downloads | How to Buy | Subscribers | Worldwide Search for All MSDN All Library Code and Downloads Product Information Knowledge Base Advanced Search Web Services and Other Distributed Technologies Home Understanding Distributed Technologies Choosing a Distributed Technology Windows Communication Foundation (Indigo) Web Services .NET Enterprise Services Message Queuing .NET Remoting COM, COM+, and DCOM InfoCard Windows Workflow Foundation BizTalk Server Downloads Community & Support Web Service Security Guidance Provides architectural, design, and implementation guidance for Web service security by using Web Services Enhancements (WSE) 3.0. Includes scenarios, patterns, decision matrices, and QuickStarts to help you make the most appropriate security decisions. Download the Powerpoint Presentations from PDC 2005 on Windows Communication Foundation Find all the Windows Communication Foundation presentations along with presentations on InfoCard, MSMQ, and other distributed technologies from PDC 2005. Implementing Always-Up-To-Date Functionality in the .NET Compact Framework by Using Web Services Find out how to implement always-up-to-date (AUTD) data synchronization functionality in the .NET Compact Framework by creating the generic ServiceWatcher class that could be used for monitoring any custom type of Web service. Matt Powell on Distributed Technologies My name is Matt Powell and I'm the content strategist here at the MSDN Web Services and Other Distributed Technologies Developer Center. Here you'll find the most recent related postings from my Weblog . New to Blogs and RSS? Check out this article . Content Strategist Wanted! I'm currently looking for a Content Strategist to work on my team here at More... Posted on Thu, 19 Jan 2006 07:12:00 GMT Comments (0) Windows Communication Foundation CTP If you haven't already heard, the WinFX January CTP released a couple days More... Posted on Thu, 19 Jan 2006 07:08:00 GMT Comments (0) Update to WSERM for WSE 3.0 Available We just posted an update to the WS-ReliableMessaging sample code that George More... Posted on Mon, 14 Nov 2005 14:14:00 GMT Comments (0) Recent Headlines Connect to Online Data Using Visio 2003 and Web Services Service Station: An XML Guru's Guide to BizTalk Server 2004, Part I Guide to Integrating with InfoCard v1.0 in WinFX Web Services Enhancements 3.0 Released! What's New in Web Services Enhancements (WSE) 3.0 .NET Framework 2.0 Released! Download Today! MSDN TV: Web Service Enhancements (WSE) 3.0 and Secure Web Services Security Briefs: Security Features in WSE 3.0 Combine the Powers of AzMan and WSE 3.0 to Protect Your Web Services Principles of Service Design: Service Patterns and Anti-Patterns Most Active Newsgroups Threads • Web Service failing URGENT • optional nillable values • WSE2 to WSE3, what to do with the pipeline ? • Consume web service using HTTP • Service to support multiple security tokens? RSS Feed Top Downloads Web Services Enhancements (WSE) 3.0 .NET Framework 2.0 SDK Windows Communication Foundation Beta 1 Web Services Enhancements (WSE) 2.0 SP3 Visual Web Developer More Essential Information Choosing a Distributed Technology Introducing Indigo: An Early Look .NET Architecture Center Top of Page Manage Your Profile | Legal | Contact Us | MSDN Flash Newsletter © 2006 Microsoft Corporation. All rights reserved. Terms of Use | Trademarks | Privacy Statement

Anti Aging

Anti-ageing creams: the facts Search iVillage for: Home Join free Horoscopes Quizzes Related Channels: Health | Entertainment | Diet and Fitness | more ... You are here iVillage.co.uk beauty skin care anti-ageing Virtual makeovers Hair care Skin care Make-up & fragrance Body basics Hints, tips and tricks Kickstart 2006 Valentine's beauty D.I.Y. detox Lovely lingerie Win a San Fran trip Fashion forecast Win a weekend in London Blistex Lip Splash Get beautiful nails Win a spa day Spa finder Morning routine quiz Make up matcher Ageing attitude quiz All tools & quizzes Beauty Entertainment Diet and Fitness more newsletters Beauty home Anti-ageing products: the bare facts by Claire Roberts It seems that wrinkles are high on our list of cosmetic concerns. According to a Boots survey, one in three women over 30 in the UK now uses an anti-ageing product. Do you look in the mirror each morning and frown at your wrinkles? If so you're not alone. In 2002 we spent £652 million on anti-ageing products and 72,000 cosmetic surgery procedures were carried out. But who can blame us? With airbrushed models at every turn, it's not hard to see why our laughter lines are, ironically, causing us untold misery. Whereas a wrinkle or two on a man 'adds character', on a woman they represent a slippery slope to old age. So is there anything we can do to stop them appearing in the first place? 'While genetic factors play some part in the overall ageing process, lifestyle has a much greater impact,' said dermatologist Dr Nicholas Lowe at a recent conference of the Royal Society of Medicine. 'About 30 per cent of facial ageing is genetic, but a lot of the rest is repetitive sunlight, smoke and other hazardous things we expose ourselves to.' So what about the creams? Are we wasting our money or can they really do anything to repair the damage? Well, the ingredients found within many anti-ageing products do have proven effects on the skin. Vitamin A can help diminish the depth of wrinkles, thanks to its light inflammatory action which 'puffs up' the skin to make wrinkles look less deep. Vitamin C has a brightening effect as it can help to boost circulation and collagen production. Alpha-hydroxy acids (AHAs or 'fruit acids') improve the skin's appearance by speeding up the shedding of old, dead cells from the skin surface. Retinoids are chemicals that make the skin produce new cells more quickly, making it thicker and more compact. After a month or two of use, the skin becomes smoother and fine wrinkles are reduced, but after six months it will be as good as it's going to get. If you discontinue use, the skin reverts to its previous condition. Has no effect on noticeable deep lines or thread veins. In theory then, creams containing these substances should work to some degree. Which? magazine decided to put anti-ageing creams to the test. It selected 12 ordinary moisturisers and 12 anti-ageing creams. Groups of four women tested each product for four weeks. None of the 96 women knew which product they were using and at the end of the trial they were asked to guess whether they'd been using a moisturiser or an anti-ageing cream. Read the results on the next page. NEXT: Put to the test In this article PAGE 1: page: 1 PAGE 2: Put to the test Created: 21/08/2003 Updated: 15/12/2003 related links ARTICLE: The beauty benefits of green tea ARTICLE: Quick-fix tips to make you look younger ARTICLE: Skin Enemies ARTICLE: What is an Alpha Hydroxy Acid (AHA) cream? ARTICLE: The beauty side effects of smoking Get the latest iVillage news on your desktop Sign up for more iVillage RSS feeds iVillage Channels Community Services About iVillage Beauty Diet & Fitness Food & Drink Health Horoscopes Money Motoring News & Showbiz Parenting Pregnancy & Baby Relationships Travel Work & Career Join free Member Centre Competitions eCards Help Instant Games Newsletters Online Dating RSS About Us Privacy Policy Site Map Terms of Service © iVillage Limited 2000-2005. All rights reserved. © iVillage inc. 1995-2005. All rights reserved. 1 -- Fabulous face! Facial washes put to the test Discover the right way to moisturise Try the better skin diet Banish the blemish The five most commonly asked skin care questions answered read this later send to a friend printer friendly

Anti Aging

Rhodiola rosea. Anti-Aging-Guide - Your plan to stay young Rhodiola rosea, Golden root - Adaptogen and Anti-Aging Medicine of 21st Century BULK SUPPLY OF DRY ROOTS, EXTRACT and TABLETS (GENUINE RUSSIAN RHODIOLA ROSEA FROM SIBERIA ) To order a dry Rhodiola Rosea extract (3% of rosavin) and tablets made of the same extract equivalent to 500 mg of dry root, please contact us by e-mail The productin is made according to GMP. Rhopdiola Rosea Bibliography RHODIOLA ROSEA (Russian Rhodiola, Golden root) - Anti-Aging Medicine of 21st Century A large proportion of all aging diseases (perhaps 70-80%) is believed to occur because the stress level is too high, and/or too long-term. High-stress modern living is probably the main factor causing chronic disease and premature aging. Fortunately, Mother Nature has an answer to this challenge - a unique class of herbal products called "adaptogens". Adaptogens have the broadest spectrum of healing properties of any herbal medicine, but their unique value is that they specifically relieve stress. History of Rhodiola rosea Adaptogens were discovered in 1947 by the Russian scientist Dr. Nicolai Lazarev, who in fact coined the name "adaptogen". Dr. Lazarev was also the mentor of Dr. Brekhman, who conducted extensive research on adaptogenic herbs. Dr Brekhman's first major focus was the now well known Panax Ginseng, also called Korean or Chinese Ginseng. This worked, but unfortunately it has a few drawbacks that have since become evident. It sometimes has side effects such as causing constipation and over-excitement which for some people is too stimulating. Dr. Brakhman soon moved on to other herbs and became recognized as the world's leading expert on adaptogens. Since then, hundreds of experimental and clinical studies on adaptogens have been done - most of them in Russia and Germany. Most of these studies have shown the outstanding stress-protective and immune system enhancing capacities of adaptogens. You may be familiar with the names of what are now called "first-generation" adaptogens: Panax Ginseng, American Ginseng, and Eleutherococcus senticosus (Siberian Ginseng). But in this article I want to tell you about a unique adaptogen of the "second generation", Rhodiola rosea (Russian Rhodiola), which is a powerful anti-aging phyto supplement with adaptogenic and anti-stress activity. In Russia, Rhodiola rosea also known as "Golden root", has been used for centuries to cope with the cold Siberian climate and stressful life. But before describing this unusual herb, let's say a few words about stress itself. History Bibliography Pharmacology Usage To buy Bulk Cultivation Details How do you feel? The main effects of adaptogens are an increased availability of energy during the day, a reduction of stressed feelings, increased endurance, greater mental alertness, and deep and restful sleep. Also, adaptogens significantly accelerate the recovery process after illness. The author of this article was ill for many years, and became weaker and weaker, despite trying a variety of medicines and supplements. Doctors could not diagnose the illness, but probably it was an autoimmune disorder, with too many symptoms to name. One day one of my friends had sent me roots of Rhodiola rosea from Moscow (Russia) and advised me to prepare Rhodiola water tea to drink. After some trial and error, I found this Siberian root worked better than anything else I had tried; and it increased the effectiveness of other supplements as well. I decided to search to find out more about this wonderful herbal adaptogen. According to modern science, adaptogens are natural plant products that increase the body's ability to cope with internal and external stress factors, and normalize the functions of the organism. They help maintain the stable internal environment inside the organism known as homeostasis. An important characteristic is that they are safe, possessing few known side effects. More info about adaptogens The three phases of stress progression 1) Alarm phase - When some new stress factor strikes the body this causes a sudden release of internal stress-hormones - corticosteroids and catheholamines. If the stress is very intense it can damage the regulatory systems of the body permanently and immediately (for example in the case of exposure to high levels of nuclear radiation); but if one is lucky, or if the person takes adaptogens, than it is possible to smoothly progress further to the "adaptation phase". 2) Adaptation phase - If the stress factor continues (for example, in sport it might be heavy athletic training) our body learns to tolerate the stressful stimulus - "adapt" - and increases its resistance to the stress factor. The "adaptation phase" is usually a safe period. The longer we can stay in the "adaptation phase", the better. 3) Finally, the exhaustion phase appears, when the body fails to fight stress anymore and simply gives up. In this "exhaustion phase", disease symptoms rapidly appear and get worse. Diseases associated with stress may appear in the first "alarm phase", but they mainly appear in the third "exhaustion phase" when the body cannot fight stress anymore. This third phase usually develops after a period of months or years. Everything depends on the duration of the "adaptation phase". Sometimes the body may be fortunate and escape this third phase altogether, provided it can keep the stress under control. It is possible to do this by taking adaptogens; they can help you to stay in the "adaptation phase" for as long as possible. Taking Rhodiola rosea extract, can make coping with stress much easier! When regularly taking Rhodiola the initial "alarm phase" of your stress will smoothly progress to the "adaptation phase". Rhodiola rosea can help you to stay in this safe "adaptation phase" for a much longer time or even permanently, so preventing your body from proceeding further to the extremely dangerous "exhaustion phase". Where to buy Scientific background Promising "second-generation" adaptogen Rhodiola rosea (Russian Rhodiola) is a perennial plant with red, pink, or yellowish flowers. It has no biological relation to the "common" rose, but due to its similar fragrance it has been used as a substitute for Attar of Roses. One of the greatest things Rhodiola does is enhance mental and physical performance. It has been widely used by Russian athletes and cosmonauts to increase energy. Rhodiola is cardio-protective, normalizing the heart rate immediately after intense exercise. It improves the nervous system and mental functions such as memory, by increasing blood-supply to the muscles and brain, and it also increases protein synthesis (1,3,4). Rhodiola rosea has extraordinary pharmacological properties as an anti-mutagen and anti-depressive agent. In this respect Rhodiola rosea is much more powerful than other adaptogens. In one study done by O.M. Duhan and colleagues (5), the anti-mutagenic activities of Panax Ginseng and of Rhodiola rosea were compared. It became clear that the extracts of Rhodiola rosea had a higher capacity to counteract gene mutations induced by various mutagens (up to about 90% inhibition in some cases). The anti-depressive and anti-stress activity of Golden root is higher than that of St. John's Wort, Ginkgo biloba and Panax Ginseng. Furthermore, Rhodiola rosea is five times less toxic than Panax ginseng. In an experiment on rats with Pliss lymphosarcoma (PLS) it was shown (6) that partial hepatectomy, a course application of Rhodiola rosea extract or combined effects inhibit the growth of tumors by 37%, 39% and 59%, respectively, and that of metastases by 42%, 50% and 75%. In one human study (7) oral administration of Rhodiola rosea extract to 12 patents with superficial bladder carcinoma (T1G1-2) improved the characteristics of the urothelial tissue integration, parameters of leukocyte integrins and T-cell immunity. The average frequency of relapses for these patients was found to fall twice. In another clinical trial 150 individuals suffering from depression took Rhodiola rosea extracts for a period of one month. At the end of that period two-thirds of them had full remission of clinical manifestations of depression, and had become more active and more sociable. Daytime weakness and general weakness disappeared. Rhodiola rosea extracts reduce significantly the yield of cells with the chromosome aberrations in vivo and inhibit unscheduled DNA synthesis induced by N-nitroso-N-methylurea in vitro (8). It is emphasized that Rhodiola rosea extracts have rejuvenative properties due to their ability to raise the efficiency of the intracell DNA repair mechanisms. Complete List of Scientific Articles (Abstracts) ROSAVIN formula Pharmacological activity - quality matters! There are products on the market that contain Rhodiola rosea. But unfortunately these products often have only limited or even no biological activity at all. Common reasons for these deficiencies are bad harvesting during the wrong season, harvesting from a climatic rigion not suitable for the plant or from a bad geographic area, harvesting wear species of the plant, also overdrying, or using an inferior extraction method. The manufacturing process also is a key factor in the preparation of a high quality adaptogenic extract, as is the selection of high quality raw materials using proper assay methods. The main active components of true Rhodiola rosea that are responsible for the extraordinary potency of Rhodiola rosea are cinnamol alcohol glycosides, especially ROSAVIN - cinnamyl-O-(6-O-L-arabinopyranosyl-D-glucopyranosid) and SALIDROSIDE . Quality Rhodiola rosea extract should contain at least 3% rosavins and 1% or less salidroside. Rhodiola rosea and immunity Rhodiola rosea stimulates the immune system in two ways: FIRST - by specific direct stimulation of immune defence (stimulates one of the most important type of immune cells - Natural Killer Cells, NK-Cells seek and destroy the infected cells on our bodies). Rhodiola rosea normalises the immune system by improving T-cell immunity (7) Rhodiola has been shown to increase the body's resistance to toxins that may accumulate during infection development. SECOND - by making a person less susceptible to stress. Scientists found out that stress suppresses immunity and destroys our resistance to various forms of bacterial or virus attack. Due to the natural killer cell's effect on tumours Rhodiola rosea may enhance B cell immunity by preventing the suppression of B cell immunity, which can occur during stress. Being under stress, a great portion of the body's energy is expended for nothing. When we are chronically exposed to stress that continually robs energy from other systems. The general effect is a lowered immune response and decreased health. For Whom Rhodiola rosea Rhodiola has been used in connection with f atigue, mental performance and athletic performance (to improve endurance) . The Russian medicine has traditionally given Rhodiola rosea to its cosmonauts, soldiers, sportsmen and ageing political leaders as an effective anti-aging medicine. Russian Rhodiola helped them to improve cognitive functions and physical performance. Prevention of development of fatigue, asthenic states, catarrhal seasonal diseases; Use in comprehensive therapy for treatment of neuroses, depression, hypotension, and other diseases; Restoration of health following recently endured communicable and somatic diseases; Increased bodily resistance to physical and mental overloads, and negative environmental effects; In sport - improved performance, resistance to strain, restoration of strength with increased physical loads; Prevention of alcohol and drug addiction; For elderly and aged persons; It may be successfully taken by drivers, flight personnel, traffic controllers, as well as other professional cohorts of people occupationally engaged in work requiring increased attention. Rhodiola rosea - natural alternative to Meridia (Reductil) slimming tablets Bulgarian researchers have demonstrated that intake of the herbal remedy Rhodiola rosea activates hormone-sensitive lipase, which plays a key role in breaking down the fat stored in adipose tissue (2) . Previous Soviet clinical studies showed that the combination of Rhodiola rosea together with physical exercise can be a powerful tool in the activation of fat-tissue lipase, resulting in the breakdown of stored fat. Georgian clinical data showed that the intake of tablets of Rhodiola rosea extract by obese subjects led to a mean weight loss of 19 pounds (11% reduction). In a control group, in contrast, the weight change was insignificant. The Bulgarian study suggests a detailed mechanism for the fat-loss effect (2). Dosage The usual amounts taken are 200 to 600 mg per day of a Rhodiola rosea extract standardized to contain 2-3% rosavins and 0.8-1% salidroside. (10) The nonstandardized amount would be 1 gram of the root three times daily (usually 5-6 tablets per day), the amount for the alcoholic extract (40% alcohol) is 5 to 40 drops (0.5 - 1 teaspoon) two to three times per day and for the tea from Rhodiola rosea roots is 1 - 2 cap per day. Rhodiola is usually taken with water before meals or at mealtimes. Please note, that Rhodiola has a more stimulating effect at lower amounts, and a more sedating effect at higher amounts. Rhodiola tea and alcoholic extract Methods of preparation Side effect and contraindications Rhodiola has been the subject of many clinical studies. No side effects or interactions have been reported. Animal studies indicate that rhodiola has a low level of toxicity. (10) Don't take rhodiola during pregnancy or while breast-feeding. There is no information available about the safety of rhodiola in pregnancy or lactation. Insomnia may be a risk with high doses of rhodiola. A high dose is considered to be daily intakes of 1,500 to 2,000 mg and above of a Rhodiola rosea standardized extract. There are no well-known drug or nutrient interactions associated with Rhodiola rosea. However, much remains to be learned about this herb and how it may interact with other adaptogens, such as Siberian ginseng, as well as with other dietary supplements. Rhodiola or Ginseng? Rhodiola rosea (Russian Rhodiola) has all the advantages of Ginseng and Eleutherococcus but lacks the tendency to cause over-excitement that may sometimes occur with ginseng, or constipation as sometimes occurs with eleutherococcus. Russian Rhodiola is FIVE times less potentially toxic, than Panax ginseng. Russian or Chinese? Be Careful! Very precise analytical tests done by HPLC did confirm, that only Rhodiola rosea of Russian origin contains key active components: Rosavin, Rosarin, Rosin . Often so-called Rhodiola rosea formulas, sold in the United States (such as "Tibetan" Rhodiola or "Chinese" Rhodiola) contain no activity at all, as these formulas lack the key ingredient Rosavins while they are high in Salidroside. Only Rhodiola rosea of Russian origin (West and North Siberia) has the highest pharmacological activity and contains key active components ROSAVIN, ROSARIN, ROSIN and SALIDROSIDE. While so-called Tibetan Rhodiola and Rhodiola rosea of Chinese origin very often do not have enough potency and contains only SALIDROSIDE. Compare content of key substances in dry roots: Chinese Rhodiola often has no activity at all, but there are other species of Rhodiola that are predomin-ating in China, such as Tibetan Rhodiola, Rhodiola quadrifida, Rhodiola kirilowii, Rhodiola heterodonta and many others. For the best quality of Rhodiola rosea click here In Conclusion Rhodiola rosea of Russian origin is now slowly but surely becoming more widely accepted in Europe and the USA as a powerful anti-aging, anti-stress formula. In today's culture of hustling and bustling, with chaos coming from every direction, I do not think we can afford to ignore this natural medicine any longer. It is in our interest to take advantage of these powerful herbs if we want to survive the demands modern life imposes on us. One does not have to be a professor or scientist to research herbs and educate oneself on how they work. The motivation depends on how much one desires to improve one's quality of life. Since life is so short, our advice is: don't wait until you have a day off, maybe next week. Why not take Russian Rhodiola as soon as possible, so your week will be more productive? Taking Rhodiola rosea, you will be better able to cope with stress! Rhodiola Rosea cultivation Rhodiola Rosea can be cultivated in two ways - from seed, or by vegetative propagation. Cultivation from seed The seeds of Rhodiola Rosea are very small (about 1.5 - 2mm long by 0.3 - 0.6mm). Growing from seed can be difficult, because the dried seeds have a low germination capacity (only about 2 - 25% of them will germinate). However, this can be improved if, prior to planting, the seeds are stored in moist sand in cool conditions for about a month. (The dry seeds are soaked in water overnight, then mixed into moist sand and kept in a suitable container). After storage for one month at a temperature between 0 - 2°C, the germination capacity will typically increase to around 75%. And by using natural stratification, sowing outdoors in the autumn (during September-October), it is possible to achieve 95-100% germination. After planting (see below), the seeds sprout after 4 - 5 days and the first leaves appear in 25 - 40 days. Vegetative propagation (root division) Rhodiola Rosea can also be propagated by root division. For this, you need to cut the underground rhizome-like roots into sections 1.5 to 15cm long, maintaining at least one bud and some hair-roots on each piece. Root division can be performed throughout the autumn months before frost, or in early spring. The cut pieces should be transplanted into soil, and after 3 weeks the plantlets should start growing. Planting The best type of soil is sandy or brown forest soil, rich in humus. The soil needs to be weeded regularly. The bed should be in an open, sunny place, and prior to planting should be treated with processed manure (3 - 5kg/sq m) or fertiliser (4 - 6kg/sq m). Adding grit, gravel, or vermiculite to the soil increases soil porosity and encourages growth; however, peat-based fertiliser should not be used. During the first month, the plants need to be carefully watered and weeded. Prick out the seedlings into individual pots when they are large enough to handle, and grow them on in the greenhouse for the first winter. Plant out in early summer of the following year. Harvesting The plants usually reach their maximum height in the third year after planting, but a minimum of 5 years must pass before the medicinal roots can be harvested. Harvesting should take place in autumn, since at this time the plant stops its vegetative growth and the dry-matter content of the root is higher. Harvesting is a simple process of digging out the roots by hand. In the case of large-scale cultivation, mechanical assistance from a cultivator machine etc. would be required. Processing the harvested roots The gathered roots should be sliced into thin strips about 10cm long, and dried in a well-ventilated drier at 40 - 50°C for 4 - 7 days. Under these conditions the original white color of the roots turns light brown. The roots should not be dried in the sun, since strong light destroys the active medicinal component! The dried root is best stored in paper packets in a cool dry place, and will keep for up to 3 years. By: John Hyatt, CA Disclaimer: The ideas, procedures and suggestions contained in this article are intended for informational purposes only. Always consult with your doctor. All materials regarding your health require medical supervision. These statements have not been evaluated by the FDA, and are not intended to diagnose, treat, or cure any disease . Selected References: 1 Maslova L.V. et al. (1994) "The cardioprotective and antiadrenergic activity of an extract of Rhodiola rosea in stress" Eksp Klin Farmakol 57(6): 61-6 2. Zakir Ramazanov, Z. et al. (1999) "New secrets of effective natural stress and weight management, using Rhodiola rosea and Rhodendron caucasicum" ATN/Safe Goods Publishing, CT. 3. Germano, C. et al. (1999) "Arctic root. The powerful new ginseng alternative" Kensington Publ.Corp. 4. Petkov, V.D. et. al. (1986) "Effects of alcohol aqueous extract from Rhodiola rosea L. roots on learning and memory" Acta Physiol Pharmacol Bulg 12(1): 3-16 5. Duhan, O.M. et al. (1999) "The antimutagenic activity of biomass extracts from the cultured cells of medicinal plants in the Ames test" Tsitol Genet Nov-Dec 33(6): 19-25 6. Udintsev SN; et.al. (1991) "The role of humoral factors of regenerating liver in the development of experimental tumours and the effect of Rhodiola rosea extract on this process" Neoplasma;38(3): 323-31 7. Bocharova OA et.al. (1995) "The effect of a Rhodiola rosea extract on the incidence of recurrences of a superficial bladder cancer (experimental clinical research)" Urol Nefrol (Mosk) Mar-Apr (2): 46-7 8. Salikhova RA et.al. (1997) "Effect of Rhodiola rosea on the yield of mutation alteration and DNA repair in bone marrow cells". Patol Fiziol Exsp Ter Oct-Dec (4): 22-4 9. Linh PT et.al. (2000) "Quantitative determination of salidroside and thyrosol from the underground part of Rhodiola rosea by high performance liquid chromatography" Arch Pharm Res Aug 23(4): 349-52 10. Brown RP, Gerbarg PL, Ramazanov Z. Rhodiola rosea: a phytomedicinal overview. Herbalgram 2002;56:40–52. Complete List of Scientific Articles (Abstracts) History Bibliography Pharmacology Usage To buy Bulk Cultivation Details Rhodiola Rosea roots for personal usage 1oz (28g) Rhodiola Rosea dry extract TABLETS for personal usage TOTAL ROSAVINS 3-4% Rhodiola Rosea seeds for personal usage 500 mg pack. BULK Genuine Russian Rhodiola rosea dry roots . ORDERS: 5 - 1000 KG To buy here To buy here To buy here *Contact us: n_elixir@hotmail.com Bulk prices for Rhodiola rosea roots: Weight Price/kg Totally 5 kg $95 $475 20 kg $64 $1.280 50 kg $54 $2.700 100 kg $48 $4.800 *We ship wordwide. Shipping charges are included in price. To the Top History Bibliography Pharmacology Usage To buy Bulk Cultivation Details

Spa Salt Souffle Body

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List Price: $26.99 Our Price: $16.99 You Save: $10.00 (37%) Quantity: Save Instantly with the Overstock.com Rewards Visa card. Click here Buy Fast. Feel Secure. ® Pay Later with Bill Me Later ® Click Here for details. Shipping: Only $2.95 for your entire order Catalog #: 10129489 Limited Inventory! Sell out Risk: VERY HIGH In stock. This product normally leaves our warehouse within 1-4 business days.* Selected Customer Reviews More Info. Tell a Friend Returns Policy Wholesale Club Returns Policy Cleanse, moisturize, and nourish your skin with the help of the Remedy Skin Care Cleansing Kit. 4-in-1 lotion provides protection and nourishes the skin in one application; cleans and removes sticky barriers and pastes Skin repair cream contains a higher level of Olivamine which delivers vital amino acids and antioxidants to the skin Complete kit works as a daily therapy to help moisturize, protect, and neutralize the effects of free radicals Shipping: This product normally leaves our warehouse within 1-4 business days.* This product is not available in US territories or APO/FPO due to shipping requirements. Materials: Olivamine Model No: MSC094204H Dimensions: 2.1 in x 3.0 in x 2.1 in * Some orders go through our fraud prevention department. If your order is selected, you will be notified and your order may be delayed an additional 3 business days. Selected Customer Reviews... Click here to write a review. 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SKIN CREAM Basic science

FROM HEART RESEARCH TO SKIN CREAM - UMass Medical School directory | contacts | index this section only "/ Home News Bureau News Makers Publications Community Relations Logos & Photography public affairs and publications : news : 2004 FROM HEART RESEARCH TO SKIN CREAM Basic science research on cellular functions yields a surprising discovery November 1, 2004 WORCESTER, Mass.-    The observation came during their work studying cellular processes within the heart.  In that effort, University of Massachusetts Medical School (UMMS) scientists James G. Dobson, Jr., PhD, professor of physiology and medicine, and Michael F. Ethier, PhD, assistant professor of medicine, were probing the effects of aging on heart function. Little did they realize that their work with adenosine would lead to the creation of a cream that improves skin tone and diminishes wrinkles. "The results took us completely by surprise, but that's what happens in basic science work," Dr. Dobson said. "The science often leads us down unexpected paths." Adenosine is a naturally occurring nucleoside found in many cells of the body.  Among its other attributes, adenosine is known to play a role in helping the heart muscle and vascular walls contract and relax. Drs. Dobson and Ethier were studying adenosine in a series of experiments probing the effect of aging on the cellular functions within the heart. "In that work, we began using dermal fibroblasts, which are skin cells, because they have well-defined aging characteristics," Dr. Ethier said. "Skin cells will only divide a certain number of times in culture, and then they die. And younger human skin cells will divide more times than older skin cells, so it's a good research model." As the experiments on heart function progressed, however, the team noticed that when adenosine was added to the skin cells, protein production within the cells increased and the cells grew in size.   The observation had a clear correlation with human skin health and wrinkles, given that it is well known that as people age their skin cells decrease in size and gradually lose their ability to synthesize proteins such as collagen and elastin. Additional work by the two scientists suggested that adenosine may mitigate another age-related effect on skin- the dramatic decline in the number of capillaries supplying blood to the dermis (the connective tissue layer of the skin located below the surface.) Growth of new capillaries is dependent on the proliferation of endothelial cells which line the inside of all blood vessels. In a series of experiments, Dobson and Ethier showed that adenosine stimulated proliferation of human endothelial cells.  Results of these experiments have been presented at meetings of The American Federation for Experimental Biology and The International Symposium on Adenosine and Adenine Nucleotides- papers on this science have been published in the Mechanisms of Ageing and Development, American Journal of Physiology and Experimental Gerontology.  In July of 2002 and in November of 2003, U.S. patents were issued to UMMS for Dobson and Ethier's technology for the application of adenosine and adenosine analogs for skin treatment.  While related patent applications were pending in territories outside of the United States, Hankook Cosmetics Company, Ltd. of Seoul, South Korea, developed an interest in the technology. In 1999, UMMS entered into a license agreement with Hankook Cosmetics Company, Ltd., for the  exclusive development, manufacture and distribution of adenosine-based skin care products within the South Korean marketplace.  In 2000, Hankook funded independent human studies in South Korea that showed topical application of adenosine decreased skin's propensity to stretch and reduced wrinkle depth. The company launched its first adenosine-based product line in 2001. "Their clinical data is quite impressive," Dobson said. "Many thousands of people in South Korea have used this product, and it works quite well." To bring adenosine-based products to a broader market, UMMS signed an exclusive license agreement in July of this year with IGI  Inc. of Buena, New Jersey, developers of the patented Novasome® transdermal delivery system that encapsulates and administers therapeutic topical products.  "IGI is pleased to add adenosine to its growing portfolio which includes PTH (1-34) for the treatment of psoriasis and PTH (7-34) for alopecia," said Frank Gerardi, IGI's chairman and CEO. "We intend to use adenosine to create a new product for the treatment of skin conditions." # # # The University of Massachusetts Medical School, one of the fastest growing medical schools in the country, has built a reputation as a world-class research institution, consistently producing noteworthy advances in clinical and basic research. UMass Medical School and its clinical partner, UMass Memorial Health Care, attract more than $154 million in research funding annually, 80 percent of which comes from federal funding sources. Research funding enables UMMS researchers to explore human disease from the molecular level to large-scale clinical trials.   Contact: Michael Cohen 508-856-2000 michael.cohen@umassmed.edu INTRANET top print This is an official Page/Publication of the University of Massachusetts Worcester Campus Public Affairs and Publications 55 Lake Avenue North Worcester, MA 01655 Questions or Comments? Email: PublicAffairs@umassmed.edu Phone: (508) 856-2000