Botox ® According to
Botox® for Migraines Drug Profiles: Botox® (botulinum toxin) CAUTION: Federal law prohibits dispensing without prescription. What is Botox ® According to a recent University Of California, San Francisco study delivered in a presentation at the American Society of Dermatologic Surgery meeting (held November 2-5, 2000), Richard Glogau, MD, UCSF professor of dermatology, reported that 75 percent of patients in his case study experienced four to six months of Migraine relief following injections of Botox® (botulinum toxin A derived from bacteria) to muscles of the face and head. Glogau's small study of 24 patients adds weight to previous reports that botulinum toxin A can relieve Migraines. Since 1992, Botox®, the same bacteria that causes deadly food poisoning, has been used in purified and diluted form to temporarily paralyze the muscles that bring the eye brows together, thereby eliminating wrinkles in this region. practice injected with botulinum toxin A in the upper third of the face for treatment of cosmetic frown lines (who coincidentally suffered from Migraines) have reported the added benefit of Migraine relief. How Botox® Is Currently Being Used To Treat Migraine Disease Following this serendipitous discovery by the University Of California, San Francisco professor Glogau and other researchers began to evaluate injection points and dosages that could alleviate Migraines. Glogau's results indicate that botulinum toxin A injected into the muscles of the brow, eyes, forehead, side of the head and back of the head near the neck (a point that earlier investigators have neglected) induce sometimes immediate Migraine relief and provide benefit for up to six months, he said. Botox® dosage in his case studies averaged 80 units per patient. There are no published, randomized, double-blind trials that show the safety and efficacy of Botox® for treatment of Migraines, Glogau said. In fact, most of the data consists of case reports and meeting abstracts. Two previous studies were presented at the 1999 meeting of the American Association for the Study of Headache (Now know as the American Headache Society). In the first study, reported by researchers at the Michigan Head Pain and Neurological Institute in Ann Arbor and Michigan State University, a one-time dose of 25 units of botulinum toxin A injected into the muscles of the brow, forehead and side of the head, reduced the frequency of Migraines, the severity of pain, vomiting, and the use of pain medications for up to three months. A 75-unit treatment yielded Migraine relief, but also side effects like eyelid drooping. In another study, reported by researchers at the University of California, Los Angeles, 51 percent of 96 patients reported complete improvement of their Migraine pain. Cost & Use of this Preventive Migraine Treatment One limitation for botulinum toxin's (Botox®) use in treating Migraines is cost. Unlike other treatments for Migraines, such as the prescription drug Imitrex® and nasal sprays (and other triptans or ergotomine drugs), Botox® injections are not covered by insurance and cost about $350 for each targeted area, (and will likely be used in multiple areas) so it appears expensive. But the cost has to be looked at divided by the 4 to 6 months that this preventive works between doses as compared to other preventive drug costs. In addition, it is important to note that prescription drugs like Imitrex® and nasal sprays are abortive treatments and not designed to replace nor use like Botox®, which is to be used as a preventative or prophylactic Migraine treatment. Possibly with some Migraineurs, they may find this botulinum toxin's use can prevent all of their attacks for up to four or more months. But for others, like many Migraine sufferers using prophylactic Migraine treatments, may discover it greatly lowers the frequency and severity of an intractable Migraineurs attacks. These individuals can then turn to abortive the prescription drugs Imitrex® (or other equally good triptans) and nasal sprays or use rescue drugs like butorphanol tartrate (Stadol®) to deal with the breakthrough attacks. So discuss this with your physician as part of an overall Migraine treatment plan including trying the Botox® for preventive treatment, as well as a good abortive treatment plan, trigger management, and pain management plan to deal with your Migraines. History of Botulinum Toxin Type A Clostridium botulinum produces 7 distinct toxins, types A through G. Botulinum toxin type A is the most studied of the 7 stereotypes produced by the anaerobic bacterium Clostridium botulinum. Minute quantities of botulinum toxin type A offer significant potential in treating a wide variety of disorders associated with muscle overactivity. Work with botulinum toxin type A as a therapeutic agent to treat human disease began in the late 1960s through the collaboration of Alan B. Scott, MD, of the Smith-Kettlewell Eye Research Foundation and Edward J. Schantz, PhD, director of food microbiology and toxicology at the University of Wisconsin. This is when botulinum toxin type A was first considered not as an agent of human sickness and disease but as a powerful therapeutic agent to treat symptoms of neurological disorders. In 1989, the rights to a form of botulinum toxin type A, currently commercialized under the trade name BOTOX®, were acquired by Allergan, Inc. In December of that same year, BOTOX® was approved for use in strabismus and blepharospasm associated with dystonia in patients 12 years of age and above. Through the collaboration of Drs. Scott and Schantz, and the pioneering efforts of Allergan, BOTOX® was added to the armamentarium of drugs used to treat these conditions. Clinical Development BOTOX® is currently in various stages of clinical development for a number of neuromuscular treatments. If successful, these treatments could offer new tools with potential to improve various patient conditions. Allergan's BOTOX® (Botulinum Toxin Type A) Purified Neurotoxin Complex is used in the treatment of certain neuromuscular disorders characterized by involuntary muscle contractions or spasms. Allergan markets BOTOX® in the United States and in 61 other countries. The approved indications for BOTOX® in the United States are for the treatment of blepharospasm (the uncontrollable contraction of the eyelid muscles that can force the eye closed and result in functional blindness) and strabismus (misalignment of the eyes) in people 12 years of age and over. For approved uses outside of the United States, please contact our global offices. Manufacture and Storage BOTOX® is supplied sterile in glass vials, each containing 100 units. BOTOX® must be diluted with sterile, nonpreserved saline immediately prior to its injection. Summary The clinical use of BOTOX® represents one of the most dramatic role reversals in modern medicine: a biologic toxin transformed into a therapeutic agent. For More Detailed Information For more detailed information regarding BOTOX® Allergans (the manufacture) webpage at: http://www.botox.com/noflash_index.html . We would like to credit the University Of California, San Francisco as an original source for part of this section. You may also wish to visit the following link for more background on the botulinum toxin Migraine studies. http://www.sciencedaily.com/releases/2000/11/001120074720.htm [ Botox® Tear Sheet ] [ Return to Drug Profiles ] [ Return to Treatment & Management ] [ Return to M.A.G.N.U.M. ] gorgeous skin Invision PowerInvision Power Services > OMG what a gorgeous skin Help - Search - Members - Calendar Full Version: OMG what a gorgeous skin Invision Power Services > Community Forums > Community General Chat MapleOne Nov 23 2005, 12:36 AM This is a Christmas based skin, but it has to be some of the best work I have ever seen http://www.ibskinned.com/forums/index.php ? Look at the icons in forum view http://www.ibskinned.com/forums/index.php?showforum=11 The only thing is they are not running 2.13 yet ------------------------------------------- Now that said http://www.ibunique.com/forums/index.php ? has been down forever and is now experiencing database errors. All the posts and skins also seem to be gone. I wonder what troubles they are having? Trish Nov 23 2005, 12:40 AM That is pretty swish like, here's the one Im going to be using this year http://www.ukcomputingservices.co.uk/skins...mages/xmas2.jpg http://www.ukcomputingservices.co.uk/skins...mages/xmas1.jpg Dan C Nov 23 2005, 01:42 AM QUOTE(MapleOne @ Nov 22 2005, 07:36 PM) The only thing is they are not running 2.13 yet We're in the process of doing that, the skins are 2.1.3-ready though. Thanks for the compliments! MapleOne Nov 23 2005, 01:58 AM What blows me away is the quality of the graphics and look at the depth around the search box on the main board. Wow I am soooooooo impressed It says the skin will be available as a non Christmas skin after the holidays. Any idea what that will look like? This may be my first skin purchase EVER TMF Group Nov 23 2005, 02:00 AM Kim and James have been the best skinners for quiet awhile. Kims gradients work and use of colur has always amazed me. Back when I was on staff for IBUnique I used to get sneak previews of stuff and each time I was left thinking...there's no way she can top that...and yet she always did. .Logan Nov 23 2005, 02:02 AM Yes, it's a very nice Christmas Skin. I haven't seen one yet this year that has beat it, Kim's style is very admirable indeed. I can't wait to see the new graphics pack that gets released (which is free to owners) to turn this into a non-christmas skin called "Club". deb1968 Nov 24 2005, 05:53 PM I have to agree with you MapleOne, that is a gorgeous skin! kewlceo Nov 24 2005, 05:58 PM It is simply stunning work. Ryan Veltidi Nov 24 2005, 06:09 PM For some reason, the skin makes me want to scroll up. As if the header is chopped off on the top of it, and I'm not seeing the entire thing. Must just be me. Starnox Nov 24 2005, 06:25 PM I personally don't like the style, but thats just me. Wilko Nov 24 2005, 07:09 PM Don't really like it, the colours are off putting. Skreid Nov 24 2005, 08:04 PM QUOTE(Ryan Veltidi @ Nov 24 2005, 11:09 AM) For some reason, the skin makes me want to scroll up. As if the header is chopped off on the top of it, and I'm not seeing the entire thing. Must just be me. Me too, seems like there is more to the header. Otherwise, excellent work God Of War Nov 24 2005, 08:14 PM That is quite a nice skin. Though yes, I agree, it seems as if some of the "Merry" and "Christmas" wording is a bit chopped. Not in half but a little bit. Brandon C Nov 24 2005, 08:38 PM Never mind. Hientc Nov 24 2005, 11:23 PM tbh, I dont like it. It is very graphical but IMO it doesn't have a christmas feeling because of the darkish colors. I'm sure a lot of work was put into it and a lot of people will enjoy it Alex Duggan Nov 25 2005, 12:33 AM Personally, I think it's a very nice skin - and in-fact I've just bought it to use on http://www.generaldiscussion.com candes Nov 25 2005, 03:47 AM Very.... very.... nice skin. Wow!!! I didn't know there were other sites out there with nice skins other than IBSkins. In fact, I could have sworn IBskinned had a construction sign on their site for a long time. I bought a 1 year membership for IBSkins. So I get a years worth of skins, and banner customizations for a year. ($75) Not a bad deal. An inexpensive way to get some nice skins. kim Nov 25 2005, 04:26 AM QUOTE(candes @ Nov 24 2005, 08:47 PM) Very.... very.... nice skin. Wow!!! Thank you, and thank you to all those who have commented one way or the other and or purchased the skin, it is lovely to get feedback QUOTE I didn't know there were other sites out there with nice skins other than IBSkins. In fact, I could have sworn IBskinned had a construction sign on their site for a long time. IBSkinn ed .com never had an under construction sign ever, and in fact the domain was registered and the site underway 5 days before neonetweb decided to change their name to ibskin. There are a number of other skinning sites than the one you mentioned, in fact most are older and more established than that site, although IBSkinn ed is relatively new, the people involved are not, and have years of experience. You might try looking at these as just a few examples: IBSkinned | IBUnique | SkinVisions | 1lotus | Extreme Pixels | Invisioncube | Transverse Styles | Pretty Flesh maddog39 Nov 25 2005, 04:52 AM Yer, that is a nice skin. I havnt looked at the post about it on that website but if its for download I might put it on my site for the holidays. candes Nov 25 2005, 05:32 AM QUOTE(kim @ Nov 24 2005, 11:26 PM) IBSkinn ed .com never had an under construction sign. Sorry.... Perhaps I remembered wrong. The names of skin sites often do sound the same. You see someone mentioned here once to go to several sites. I found one had construction going on, and another I had trouble finding the skins at. Maybe the second was yours since I did bookmartk it to check out later. And thanks for all the links. I will check them out. Debbie Nov 25 2005, 07:21 AM I need a Xmas skin for 2.0.4 and 2.1.3! Gypsie Nov 25 2005, 01:57 PM [quote name='MapleOne' date='Nov 23 2005, 10:06 AM' post='1322213'] This is a Christmas based skin, but it has to be some of the best work I have ever seen http://www.ibskinned.com/forums/index.php ? Look at the icons in forum view http://www.ibskinned.com/forums/index.php?showforum=11 Totally agree.....the best one I've seen Top marks for that one Way to go Aaron Nov 26 2005, 11:08 PM its a cool skin i use it on my site Bb Nov 28 2005, 11:08 PM The extent of my christmas skin will be a little sled or something in the top right of the page and maybe a bit of tinsel wrapped round the rawkstar. But that is a very nice skin, but... as i hate christmas ( ) i don't want a christmas theme. It's one of the nicest themes (and a complete theme, not a few simple colour changes) i've seen. well done! Andrew Nov 28 2005, 11:26 PM Yes it is an amazing sking Just wish I would receive my registration e-mail at their forums Arts&Faith Nov 30 2005, 06:04 PM I like it, and might pick it up myself -- when it's Christmas, of course. We're still a few weeks away... Sauren Nov 30 2005, 11:01 PM I may get it as well... very tempting. This is a "lo-fi" version of our main content. To view the full version with more information, formatting and images, please click here . Invision Power Board © 2001-2006 Invision Power Services, Inc. skin treatment options. OurPenn Plastic Surgery: Skin Care Program Appointments | Medical Services | Health Information | Find a Doctor Search: Overview | Cosmetic Surgery | Reconstructive Surgery | Skin Care Program Overview Procedures Skin Care Program Overview Services Why choose Penn? For more than 10 years, aestheticians of the Skin Care Program have offered non-surgical techniques, treatments and products to rejuvenate the skin. They present the latest anti-aging therapies, as well as skin care options for those with acne, rosacea and sensitive skin. The program's clinical services are also excellent for those who have had or plan to invest in cosmetic surgery. Patients with healthy skin before surgery recover more quickly and have healthier skin after their procedure. Services During your first consultation with an aesthetician, or skin care professional, be prepared to discuss the concerns you have about your skin. The aesthetician will listen, examine your skin to determine your skin type, ask about medicines you may be taking that effect your skin and talk with you about the best options for skin rejuvenation. The Skin Care Program offers a wide range of services, including: Camouflage make-up Chemical peels Intense pulsed light (IPL) Laser hair removal Microdermabrasion Micropigmentation Why choose Penn? Whether you are interested in a specific procedure or just want help looking your very best, the Skin Care Program offers a relaxed and caring environment. Patients see one of four state-licensed aestheticians trained in clinical skin treatment options. Our caring team will be attentive to your needs and concerns as they help you learn a new approach to skin care. Our aestheticians are among the area’s best: Betsy Rubenstone, Certified Medical Aesthetician; Medical Assistant; past-president, Society of Plastic Surgical Skin Care Specialists JoEllen Cozen, Certified Medical Aesthetician Amanda Gross, Certified Medical Aesthetician Jeanne Vos, Certified Medical Aesthetician The Skin Care Program carries only physician-recommended skin products that we believe to be effective, including: La Roche-Posay BioMedic Perricone Cosmeceuticals SkinCeuticals SkinMedica For more information or to make an appointment, please call 1-800-789-PENN (7366) and ask for the Plastic Surgery Skin Care Program. Need an appointment? Request one online 24 hours a day, 7 days a week; or call 1-800-789-PENN (7366) to speak to a referral counselor. Related Links Find a Plastic Surgeon Request an Appointment Online or call 1-800-789-PENN (7366) Visitor Information Encyclopedia Articles about Plastic Surgery About UPHS Contact Us Site Map Privacy Statement Legal Disclaimer Terms of Use The University of Pennsylvania Health System, Philadelphia, PA © 2006, The Trustees of the University of Pennsylvania Great SkinGreat Skin;Skincare:Acne treatment, food and nutrition, Cellex c, whiteheads, acne vulgaris, skincare products, acne treatment, blackheads, adult acne, sebaceous glands and Obagi Physicians GreatSkin® Clinics Clinics Skincare Services and Procedures Physicians GreatSkin ® Clinics offers a new concept in skin renovation and rejuvenation. Through scientific and clinical processes using the combined talents of both skin estheticians and physicians , we produce the growth of fresh new skin for you. Through custom-tailored procedures with clinical skincare products , chemical peels , blue peels , and laser skin resurfacing with Coherent's Ultra Pulse Aesthetic Laser, we gently create a new, fresh skin surface and show you how to keep it. The Coherent Ultra Pulse is the first and only laser to be granted marketing clearance from the FDA for increased collagen as a result of laser resurfacing. Clients Before & After Resurfacing Results We alleviate age rhytids (wrinkles), sun damage, Acne scarring, hyperpigmentation and, in general, restore vibrant, tight, elastic new skin. Our process results in a natural healing, "growing away" wrinkles and skin imperfections by fertilizing the dermis with growth stimulation products, removing old, damaged skin so that fresh, new skin proliferates in a matter of days. View a short RealVideo on GreatSkin® Clinics Hi Bandwidth Low Bandwidth Before and After Laser Skin Resurfacing Results: Client #1: A 48 year old female - extensive sun damage. Client #2: A 78 year old female - age related. Client #3: A 65 year old female - age, tobacco and extensive sun damage. Client #4: A 71 year old woman - age and extensive sun damage. Client #5: A 32 year old woman - premature sun-induced aging. Client #6: A 23 year old woman - Acne scarring. Client #7: A 68 year old woman - age and sun damage. Dr. Van Wormer is a Board Certified Laser Surgeon - the only one in Texas or New Mexico, and one of only 300 in the United States. Want more information on the Laser Skin Resurfacing procedure? Click Here! Interested in pre-laser or facial Plastic Surgery preparation? Or in great post-laser or Plastic Surgery skincare? Click Here . 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